Methanol → 2-Methyl-5-tosyl-2,5-diazabicyclo[2.2.1]heptane

HRID 2144018Notes

Reaction equation

HRID 2144018 reaction equation
[CH3:29][NH2:30].[CH3:31][OH:32].[c:1]1([CH3:28])[cH:2][cH:3][c:4]([S:7](=[O:8])(=[O:9])[N:10]2[CH:11]([CH2:26][Cl:27])[CH2:12][CH:13]([O:15][S:16]([c:17]3[cH:18][cH:19][c:20]([CH3:21])[cH:22][cH:23]3)(=[O:24])=[O:25])[CH2:14]2)[cH:5][cH:6]1>>[c:1]1([CH3:28])[cH:2][cH:3][c:4]([S:7](=[O:8])(=[O:9])[N:10]2[CH:11]3[CH2:12][CH:13]([CH2:14]2)[N:30]([CH3:29])[CH2:26]3)[cH:5][cH:6]1

Participants

4

Reactant 3

HCID 887MethanolHCID 6329MethylamineHCID 15629274[5-(Chloromethyl)-1-(4-methylphenyl)sulfonylpyrrolidin-3-yl] 4-methylbenzenesulfonate

Product 1

HCID 156292772-Methyl-5-tosyl-2,5-diazabicyclo[2.2.1]heptane

Sources & evidence

ORD record
ord-50ae3094832148b1a596040d0cda4d59
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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