Sodium ion → Tert-butyl 4-[4-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrrolo[2,3-d]pyrimidin-7-yl]piperidine-1-carboxylate

HRID 2144149Notes

Reaction equation

HRID 2144149 reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][c:7]2[c:11]([cH:12][cH:13]1)[NH:10][CH2:9][CH2:8]2.[CH3:37][N:38]([CH3:39])[CH:40]=[O:41].[Cl:14][c:15]1[c:16]2[c:17]([n:18][cH:19][n:20]1)[n:21]([CH:24]1[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]1)[cH:22][cH:23]2.[H-:42].[Na+:43].[OH2:44]>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][c:7]2[c:11]([cH:12][cH:13]1)[N:10]([c:15]1[c:16]3[c:17]([n:18][cH:19][n:20]1)[n:21]([CH:24]1[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]1)[cH:22][cH:23]3)[CH2:9][CH2:8]2

Participants

7

Reactant 6

HCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 166653HydrideHCID 27361365-(Methanesulfonyl)-2,3-dihydro-1H-indoleHCID 58270310tert-butyl 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)piperidine-1-carboxylate

Product 1

HCID 58074082Tert-butyl 4-[4-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrrolo[2,3-d]pyrimidin-7-yl]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-13e94d77b65d4da19dc104828a9406fb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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