Water → 2-(1-Ethoxycarbonyl-2-vinyl-cyclopropylcarbamoyl)-4-[2-(3-fluoro-phenyl)-7-methoxy-8-methyl-quinazolin-4-yloxy]-cyclopentanecarboxylic acid
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[CH:8]1[CH:9]([C:34]([NH:35][C:36]2([C:41](=[O:42])[O:43][CH2:44][CH3:45])[CH:37]([CH:39]=[CH2:40])[CH2:38]2)=[O:46])[CH2:10][CH:11]([O:13][c:14]2[n:15][c:16](-[c:27]3[cH:28][c:29]([F:33])[cH:30][cH:31][cH:32]3)[n:17][c:18]3[c:19]([CH3:26])[c:20]([O:24][CH3:25])[cH:21][cH:22][c:23]23)[CH2:12]1.[Cl:48][CH2:49][Cl:50].[F:51][C:52]([F:53])([F:54])[C:55]([OH:56])=[O:57].[OH2:47]>>[O:5]=[C:6]([OH:7])[CH:8]1[CH:9]([C:34]([NH:35][C:36]2([C:41](=[O:42])[O:43][CH2:44][CH3:45])[CH:37]([CH:39]=[CH2:40])[CH2:38]2)=[O:46])[CH2:10][CH:11]([O:13][c:14]2[n:15][c:16](-[c:27]3[cH:28][c:29]([F:33])[cH:30][cH:31][cH:32]3)[n:17][c:18]3[c:19]([CH3:26])[c:20]([O:24][CH3:25])[cH:21][cH:22][c:23]23)[CH2:12]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-fb2c14a36f57401b8e9a8d1fb5949b4f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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