Diethyl Ether → Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate
Reaction equation
[Al+3:20].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:12][CH2:13]1.[CH3:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30].[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[H-:19].[H-:22].[H-:23].[H-:24].[Li+:21]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][OH:15])[CH2:12][CH2:13]1Participants
7
Sources & evidence
- ORD record
- ord-ff67e51ba8b74b3caddc04462b0807f9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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