Water → Tert-butyl [(2-isobutyl-4-(4-methylphenyl)-6-{2-[(methylsulfonyl)amino]-2-oxoethoxy}quinolin-3-yl)methyl]carbamate

HRID 2144428Notes

Reaction equation

HRID 2144428 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][c:10]1[c:11]([CH2:32][CH:33]([CH3:34])[CH3:35])[n:12][c:13]2[cH:14][cH:15][c:16]([O:27][CH2:28][C:29](=[O:30])[OH:31])[cH:17][c:18]2[c:19]1-[c:20]1[cH:21][cH:22][c:23]([CH3:26])[cH:24][cH:25]1.[CH3:36][S:37](=[O:38])(=[O:39])[NH2:40].[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[OH2:41]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][c:10]1[c:11]([CH2:32][CH:33]([CH3:34])[CH3:35])[n:12][c:13]2[cH:14][cH:15][c:16]([O:27][CH2:28][C:29](=[O:30])[NH:40][S:37]([CH3:36])(=[O:38])=[O:39])[cH:17][c:18]2[c:19]1-[c:20]1[cH:21][cH:22][c:23]([CH3:26])[cH:24][cH:25]1

Participants

5

Reactant 4

HCID 962WaterHCID 6228DimethylformamideHCID 72879MethanesulfonamideHCID 68829615{[3-{[(Tert-butoxycarbonyl)amino]methyl}-2-isobutyl-4-(4-methylphenyl)quinolin-6-yl]oxy}acetic acid

Product 1

HCID 69152932Tert-butyl [(2-isobutyl-4-(4-methylphenyl)-6-{2-[(methylsulfonyl)amino]-2-oxoethoxy}quinolin-3-yl)methyl]carbamate

Sources & evidence

ORD record
ord-a928209bb38e479386172978a81d159f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…