Dimethyl Sulfoxide → Trans-N-(4-acetylcyclohexyl)-2-chloro-5-(trifluoromethyl)benzamide

HRID 2144565Notes

Reaction equation

HRID 2144565 reaction equation
[CH3:46][S:47]([CH3:48])=[O:49].[CH:24]([N:25]([CH2:26][CH3:27])[CH:28]([CH3:29])[CH3:30])([CH3:31])[CH3:32].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][CH:7]2[CH2:8][CH2:9][CH:10]([CH:13]([CH3:14])[OH:15])[CH2:11][CH2:12]2)[cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]1.[Cl:43][CH2:44][Cl:45].[S:39](=[O:40])(=[O:41])=[O:42].[n:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][CH:7]2[CH2:8][CH2:9][CH:10]([C:13]([CH3:14])=[O:15])[CH2:11][CH2:12]2)[cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]1

Participants

7

Reactant 6

HCID 679Dimethyl SulfoxideHCID 1049PyridineHCID 6344DichloromethaneHCID 24682Sulfur trioxideHCID 81531DiisopropylethylamineHCID 178466750HCID 178466750, compound

Product 1

HCID 67184771Trans-N-(4-acetylcyclohexyl)-2-chloro-5-(trifluoromethyl)benzamide

Sources & evidence

ORD record
ord-97f75c3c80214fc59c5101c7b6c6d601
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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