Tetrahydrofuran → N-(3-(3-bromophenyl)-3-hydroxypropyl)-2,2,2-trifluoroacetamide
Reaction equation
[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[F:13][C:14]([C:15](=[O:16])[O:17][CH2:18][CH3:19])([F:20])[F:21].[NH2:1][CH2:2][CH2:3][CH:4]([OH:5])[c:6]1[cH:7][c:8]([Br:12])[cH:9][cH:10][cH:11]1>>[NH:1]([CH2:2][CH2:3][CH:4]([OH:5])[c:6]1[cH:7][c:8]([Br:12])[cH:9][cH:10][cH:11]1)[C:15]([C:14]([F:13])([F:20])[F:21])=[O:16]Participants
4
Sources & evidence
- ORD record
- ord-70b27d100450490c8b9e5e6b7b9a7a93
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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