Sodium ion → methyl (RS)-5-[3-(4-chlorobenzyloxy)phenyl]-4-(2-methylphenyl)-5-oxopentanoate

HRID 214474Notes

Reaction equation

HRID 214474 reaction equation
[CH3:35][N:36]([CH3:37])[CH:38]=[O:39].[Cl:26][c:27]1[cH:28][cH:29][c:30]([CH2:31][Cl:32])[cH:33][cH:34]1.[H-:24].[Na+:25].[OH:1][c:2]1[cH:3][c:4]([C:8]([CH:9]([CH2:10][CH2:11][C:12](=[O:13])[O:14][CH3:15])[c:16]2[c:17]([CH3:22])[cH:18][cH:19][cH:20][cH:21]2)=[O:23])[cH:5][cH:6][cH:7]1>>[O:1]([c:2]1[cH:3][c:4]([C:8]([CH:9]([CH2:10][CH2:11][C:12](=[O:13])[O:14][CH3:15])[c:16]2[c:17]([CH3:22])[cH:18][cH:19][cH:20][cH:21]2)=[O:23])[cH:5][cH:6][cH:7]1)[CH2:31][c:30]1[cH:29][cH:28][c:27]([Cl:26])[cH:34][cH:33]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 77231-Chloro-4-(chloromethyl)benzeneHCID 166653HydrideHCID 10805064methyl (RS)-5-(3-hydroxyphenyl)-5-oxo-4-(2-methylphenyl)pentanoate

Product 1

HCID 10812856methyl (RS)-5-[3-(4-chlorobenzyloxy)phenyl]-4-(2-methylphenyl)-5-oxopentanoate

Sources & evidence

ORD record
ord-0b529544dbae4fda84966f2f3c6702ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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