Tetrahydrofuran → Methyl 6-[1-(4-chlorophenyl)-pyrazol-5-yl]-5-methyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazine-2-carboxylate
Reaction equation
[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[Cl:24][c:25]1[cH:26][cH:27][c:28](-[n:31]2[n:32][cH:33][cH:34][c:35]2[Sn:36]([CH2:37][CH2:38][CH2:39][CH3:40])([CH2:41][CH2:42][CH2:43][CH3:44])[CH2:45][CH2:46][CH2:47][CH3:48])[cH:29][cH:30]1.[I:1][c:2]1[c:3]([CH3:23])[n:4](-[c:13]2[cH:14][c:15]([C:19]([F:20])([F:21])[F:22])[cH:16][cH:17][cH:18]2)[c:5](=[O:12])[c:6]([C:8](=[O:9])[O:10][CH3:11])[n:7]1>>[c:2]1(-[c:35]2[n:31](-[c:28]3[cH:27][cH:26][c:25]([Cl:24])[cH:30][cH:29]3)[n:32][cH:33][cH:34]2)[c:3]([CH3:23])[n:4](-[c:13]2[cH:14][c:15]([C:19]([F:20])([F:21])[F:22])[cH:16][cH:17][cH:18]2)[c:5](=[O:12])[c:6]([C:8](=[O:9])[O:10][CH3:11])[n:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-994597dd6dfe4e4297f94ee4d7f41b56
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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