Potassium Cation → N-[4-Amino-2-fluoro-3-(2-hydroxyethyl)phenyl]-2,2-difluoro-2-(4-fluoronaphthyl)acetamide
Reaction equation
[C:1](=[O:2])([CH3:3])[O:4][CH2:5][CH2:6][c:7]1[c:8]([NH2:31])[cH:9][cH:10][c:11]([NH:14][C:15]([C:16]([c:17]2[cH:18][cH:19][c:20]([F:27])[c:21]3[cH:22][cH:23][cH:24][cH:25][c:26]23)([F:28])[F:29])=[O:30])[c:12]1[F:13].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:43][OH:44].[K+:37].[K+:38].[O-:39][C:40]([O-:41])=[O:42].[OH2:45]>>[OH:4][CH2:5][CH2:6][c:7]1[c:8]([NH2:31])[cH:9][cH:10][c:11]([NH:14][C:15]([C:16]([c:17]2[cH:18][cH:19][c:20]([F:27])[c:21]3[cH:22][cH:23][cH:24][cH:25][c:26]23)([F:28])[F:29])=[O:30])[c:12]1[F:13]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f9667346b76c43779212caddfbe9b1bd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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