Pyridine → 1-{[5-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}-5-methyl-3-phenylpyrrolidin-3-ol

HRID 2144880Notes

Reaction equation

HRID 2144880 reaction equation
[B-:35]([F:36])([F:37])([F:38])[F:39].[CH3:22][CH:23]1[CH2:24][C:25]([OH:28])([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[CH2:26][NH:27]1.[F:7][c:8]1[cH:9][cH:10][c:11](-[c:14]2[c:15]([C:19](=[O:20])[OH:21])[cH:16][n:17][nH:18]2)[cH:12][cH:13]1.[O:57]=[CH:58][N:59]([CH3:60])[CH3:61].[cH:1]1[cH:2][cH:3][n:4][cH:5][cH:6]1.[n:40]1([O:41][C:42]([N:43]([CH3:44])[CH3:45])=[N+:46]([CH3:47])[CH3:48])[c:49]2[cH:50][cH:51][cH:52][cH:53][c:54]2[n:55][n:56]1>>[F:7][c:8]1[cH:9][cH:10][c:11](-[c:14]2[c:15]([C:19](=[O:21])[N:27]3[CH:23]([CH3:22])[CH2:24][C:25]([OH:28])([c:29]4[cH:30][cH:31][cH:32][cH:33][cH:34]4)[CH2:26]3)[cH:16][n:17][nH:18]2)[cH:12][cH:13]1

Participants

7

Reactant 6

HCID 1049PyridineHCID 6228DimethylformamideHCID 26255TetrafluoroborateHCID 130500O-benzotriazol-1-yl-tetramethyluroniumHCID 30513955-Methyl-3-phenyl-pyrrolidin-3-olHCID 34654723-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid

Product 1

HCID 591701591-{[5-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}-5-methyl-3-phenylpyrrolidin-3-ol

Sources & evidence

ORD record
ord-0007f297da2944ba969bf60042e67c27
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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