反应详情

A mixture of 2-fluoro-4-methylsulphonylbenzoic acid (6.0 g) and thionyl chloride were stirred and heated at reflux for 2 hours. The mixture was cooled and evaporated to dryness. Toluene was added and the solvent re-evaporated to give 2-fluoro-4-methylsulphonylbenzoyl chloride (6.5 g) as a brown solid which was not further purified.

1. temperatureheated
2. temperatureat reflux for 2 hours
3. temperatureThe mixture was cooled
4. customevaporated to dryness
5. additionToluene was added
6. customthe solvent re-evaporated