Chloroform → 3-[[N-(2-amino-4,5-difluorobenzoyl)glycyl]aminomethyl]-1-(4-chlorobenzyl)pyrrolidine
Reaction equation
[CH3:55][C:56]([OH:57])([CH3:58])[CH3:59].[CH:32]([N:33]=[C:34]=[N:35][CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][N:7]2[CH2:8][CH:9]([CH2:12][NH:13][C:14]([CH2:15][NH2:16])=[O:17])[CH2:10][CH2:11]2)[cH:18][cH:19]1.[Cl:51][CH:52]([Cl:53])[Cl:54].[NH2:20][c:21]1[c:22]([C:23](=[O:24])[OH:25])[cH:26][c:27]([F:31])[c:28]([F:30])[cH:29]1.[OH:41][n:42]1[c:43]2[c:44]([cH:45][cH:46][cH:47][cH:48]2)[n:49][n:50]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][N:7]2[CH2:8][CH:9]([CH2:12][NH:13][C:14]([CH2:15][NH:16][C:23]([c:22]3[c:21]([NH2:20])[cH:29][c:28]([F:30])[c:27]([F:31])[cH:26]3)=[O:24])=[O:17])[CH2:10][CH2:11]2)[cH:18][cH:19]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d94bcf23ba1f4dd0b8012f780f3cd63c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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