Acetate → 5'-Bromo-2'-chloro-2-methyl-[3,4']bipyridinyl

HRID 2145263Notes

Reaction equation

HRID 2145263 reaction equation
[Br:21][c:22]1[c:23]([I:29])[cH:24][c:25]([Cl:28])[n:26][cH:27]1.[CH3:17][C:18](=[O:19])[O-:20].[CH3:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1[O:8][S:9]([C:10]([F:11])([F:12])[F:13])(=[O:14])=[O:15].[CH3:36][N:37]([CH3:38])[CH:39]=[O:40].[K+:16].[Na+:30].[Na+:31].[O-:32][C:33](=[O:34])[O-:35].[OH2:41]>>[CH3:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:23]1[c:22]([Br:21])[cH:27][n:26][c:25]([Cl:28])[cH:24]1

Participants

9

Reactant 8

HCID 175AcetateHCID 813Potassium CationHCID 923Sodium ion2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 107764652-Methylpyridin-3-yl trifluoromethanesulfonateHCID 218651405-Bromo-2-chloro-4-iodopyridine

Product 1

HCID 210836365'-Bromo-2'-chloro-2-methyl-[3,4']bipyridinyl

Sources & evidence

ORD record
ord-276a0823fa6045edbbb120a2147a18a3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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