Hydrogen Bromide → 4'-(2-Amino-4-thiazolyl)-N-cyclopropyl-6-methyl[1,1'-biphenyl]-3-carboxamide

HRID 2145287Notes

Reaction equation

HRID 2145287 reaction equation
[Br:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]([NH2:14])[s:12][cH:13]2)[cH:7][cH:8]1.[BrH:1].[CH:15]1([NH:18][C:19]([c:20]2[cH:21][c:22]([B:27]3[O:28][C:29]([CH3:30])([CH3:31])[C:32]([CH3:33])([CH3:34])[O:35]3)[c:23]([CH3:26])[cH:24][cH:25]2)=[O:36])[CH2:16][CH2:17]1>>[c:3]1(-[c:22]2[cH:21][c:20]([C:19]([NH:18][CH:15]3[CH2:16][CH2:17]3)=[O:36])[cH:25][cH:24][c:23]2[CH3:26])[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]([NH2:14])[s:12][cH:13]2)[cH:7][cH:8]1

Participants

4

Reactant 3

HCID 260Hydrogen BromideHCID 6206834-(4-Bromophenyl)-1,3-thiazol-2-amineHCID 21914577N-cyclopropyl-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

Product 1

HCID 99751254'-(2-Amino-4-thiazolyl)-N-cyclopropyl-6-methyl[1,1'-biphenyl]-3-carboxamide

Sources & evidence

ORD record
ord-e7f6eda3be92444f819e42a944960941
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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