Bicarbonate Ion → (3-Bromo-4-methoxy-phenyl)-(2,3-dihydro-pyrido[4,3-b][1,4]oxazin-4-yl)-methanone

HRID 2145776Notes

Reaction equation

HRID 2145776 reaction equation
[Br:11][c:12]1[cH:13][c:14]([C:15](=[O:16])[OH:17])[cH:18][cH:19][c:20]1[O:21][CH3:22].[C:28](=[O:29])([O-:30])[OH:31].[Na+:32].[O:1]1[c:2]2[c:3]([cH:7][n:8][cH:9][cH:10]2)[NH:4][CH2:5][CH2:6]1.[P:23]([Cl:24])([Cl:25])([Cl:26])=[O:27]>>[O:1]1[c:2]2[c:3]([cH:7][n:8][cH:9][cH:10]2)[N:4]([C:15]([c:14]2[cH:13][c:12]([Br:11])[c:20]([O:21][CH3:22])[cH:19][cH:18]2)=[O:16])[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 24813Phosphorus oxychlorideHCID 668363-Bromo-4-methoxybenzoic acidHCID 218859502H,3H,4H-pyrido[4,3-b][1,4]oxazine

Product 1

HCID 66936511(3-Bromo-4-methoxy-phenyl)-(2,3-dihydro-pyrido[4,3-b][1,4]oxazin-4-yl)-methanone

Sources & evidence

ORD record
ord-7b3669d4831f425b84c6799919e41fdd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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