Tetrahydrofuran → 6-(Bromomethyl)pyrido[3,2-d]pyrimidine-2,4-diamine

HRID 2145912Notes

Reaction equation

HRID 2145912 reaction equation
[CH2:19]1[O:20][CH2:21][CH2:22][CH2:23]1.[NH2:1][c:2]1[n:3][c:4]([NH2:14])[c:5]2[c:6]([n:7]1)[cH:8][cH:9][c:10]([CH2:12][OH:13])[n:11]2.[P:15]([Br:16])([Br:17])[Br:18]>>[NH2:1][c:2]1[n:3][c:4]([NH2:14])[c:5]2[c:6]([n:7]1)[cH:8][cH:9][c:10]([CH2:12][Br:16])[n:11]2

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 24614Phosphorus tribromideHCID 13345225(2,4-Diaminopyrido[3,2-d]pyrimidin-6-yl)methanol

Product 1

HCID 133452266-(Bromomethyl)pyrido[3,2-d]pyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-6be3a3fc4f3d4fda9bae883f657ed356
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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