Methanol → 7-[5-(5-Chloro-2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-3-(2-thienyl)-6,7-dihydro-5H-[1,2,4]triazolo[3,4-b][1,3]thiazine

HRID 2146045Notes

Reaction equation

HRID 2146045 reaction equation
[CH3:1][S:2]([O:3][CH2:6][CH2:7][n:8]1[c:9]([S:18][CH2:19][c:20]2[n:21][o:22][c:23](-[c:25]3[c:26]([F:32])[cH:27][cH:28][c:29]([Cl:31])[cH:30]3)[n:24]2)[n:10][n:11][c:12]1-[c:13]1[s:14][cH:15][cH:16][cH:17]1)(=[O:4])=[O:5].[CH3:35][OH:36].[H-:33].[Na+:34].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41]>>[CH2:6]1[CH2:7][n:8]2[c:9]([n:10][n:11][c:12]2-[c:13]2[s:14][cH:15][cH:16][cH:17]2)[S:18][CH:19]1[c:20]1[n:21][o:22][c:23](-[c:25]2[c:26]([F:32])[cH:27][cH:28][c:29]([Cl:31])[cH:30]2)[n:24]1

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 6228DimethylformamideHCID 166653HydrideHCID 866025852-[3-({[5-(5-Chloro-2-fluorophenyl)-1,2,4-oxadiazol-3-yl]methyl}thio)-5-(2-thienyl)-4H-1,2,4-triazol-4-yl]ethyl methanesulfonate

Product 1

HCID 113391437-[5-(5-Chloro-2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-3-(2-thienyl)-6,7-dihydro-5H-[1,2,4]triazolo[3,4-b][1,3]thiazine

Sources & evidence

ORD record
ord-c6fa29fff0c849c69da81bd64ff1d185
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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