Water → 5,6-Dichloro-2-[4-methoxy-3-(thiophene-2-sulfonylamino)-phenyl]-benzoimidazole-1-carboxylic acid benzyl ester

HRID 2146200Notes

Reaction equation

HRID 2146200 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[n:11]1[c:12](-[c:22]2[cH:23][c:24]([NH2:30])[c:25]([O:28][CH3:29])[cH:26][cH:27]2)[n:13][c:14]2[c:15]1[cH:16][c:17]([Cl:21])[c:18]([Cl:20])[cH:19]2.[OH2:46].[cH:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1.[s:37]1[c:38]([S:42](=[O:43])(=[O:44])[Cl:45])[cH:39][cH:40][cH:41]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[n:11]1[c:12](-[c:22]2[cH:23][c:24]([NH:30][S:42]([c:38]3[s:37][cH:41][cH:40][cH:39]3)(=[O:43])=[O:44])[c:25]([O:28][CH3:29])[cH:26][cH:27]2)[n:13][c:14]2[c:15]1[cH:16][c:17]([Cl:21])[c:18]([Cl:20])[cH:19]2

Participants

5

Reactant 4

HCID 962WaterHCID 1049PyridineHCID 855182-Thiophenesulfonyl chlorideHCID 102751152-(3-Amino-4-methoxy-phenyl)-5,6-dichloro-benzoimidazole-1-carboxylic acid benzyl ester

Product 1

HCID 207608855,6-Dichloro-2-[4-methoxy-3-(thiophene-2-sulfonylamino)-phenyl]-benzoimidazole-1-carboxylic acid benzyl ester

Sources & evidence

ORD record
ord-a467c6557f1840f4adddb87394a4ceb6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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