Dichloromethane → (4-Nitrophenyl)methyl 4-[[1-[(4-nitrophenyl)methoxycarbonyl]-4-tritylsulfanylpyrrolidin-2-yl]methyl]piperazine-1-carboxylate

HRID 2146403Notes

Reaction equation

HRID 2146403 reaction equation
[CH3:46][CH2:47][N:48]([CH2:49][CH3:50])[CH2:51][CH3:52].[Cl:67][CH2:68][Cl:69].[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7]([CH2:8][O:9][C:10](=[O:11])[N:12]2[CH:13]([CH2:37][N:38]3[CH2:39][CH2:40][NH:41][CH2:42][CH2:43]3)[CH2:14][CH:15]([S:17][C:18]([c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)([c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)[c:31]3[cH:32][cH:33][cH:34][cH:35][cH:36]3)[CH2:16]2)[cH:44][cH:45]1.[N+:53](=[O:54])([O-:55])[c:56]1[cH:57][cH:58][c:59]([CH2:60][O:61][C:62](=[O:63])[Cl:64])[cH:65][cH:66]1>>[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7]([CH2:8][O:9][C:10](=[O:11])[N:12]2[CH:13]([CH2:37][N:38]3[CH2:39][CH2:40][N:41]([C:62]([O:61][CH2:60][c:59]4[cH:58][cH:57][c:56]([N+:53](=[O:54])[O-:55])[cH:66][cH:65]4)=[O:63])[CH2:42][CH2:43]3)[CH2:14][CH:15]([S:17][C:18]([c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)([c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)[c:31]3[cH:32][cH:33][cH:34][cH:35][cH:36]3)[CH2:16]2)[cH:44][cH:45]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 782054-Nitrobenzyl chloroformateHCID 178525205HCID 178525205, compound

Product 1

HCID 19770184(4-Nitrophenyl)methyl 4-[[1-[(4-nitrophenyl)methoxycarbonyl]-4-tritylsulfanylpyrrolidin-2-yl]methyl]piperazine-1-carboxylate

Sources & evidence

ORD record
ord-f50371ff05a847d8b976d10c7c87bf82
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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