Water → tert-Butyl 5-bromo-3-oxo-3H-spiro[benzofuran-2,4'-piperidine]-1'-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([OH:14])([C:15]([c:16]2[c:17]([F:23])[cH:18][cH:19][c:20]([Br:22])[cH:21]2)=[O:24])[CH2:12][CH2:13]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[OH2:25]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]2([CH2:12][CH2:13]1)[O:14][c:17]1[c:16]([cH:21][c:20]([Br:22])[cH:19][cH:18]1)[C:15]2=[O:24]Participants
4
Sources & evidence
- ORD record
- ord-960619f250db4b259074c4613819b46c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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