Piperazine → 6-Chloro-4-(piperazin-1-yl)pyrido[3,2-d]pyrimidine

HRID 2146723Notes

Reaction equation

HRID 2146723 reaction equation
[CH2:19]1[O:20][CH2:21][CH2:22][O:23][CH2:24]1.[CH2:1]1[CH2:2][NH:3][CH2:4][CH2:5][NH:6]1.[Cl:7][c:8]1[c:9]2[c:10]([n:11][cH:12][n:13]1)[cH:14][cH:15][c:16]([Cl:18])[n:17]2>>[CH2:1]1[CH2:2][N:3]([c:8]2[c:9]3[c:10]([n:11][cH:12][n:13]2)[cH:14][cH:15][c:16]([Cl:18])[n:17]3)[CH2:4][CH2:5][NH:6]1

Participants

4

Reactant 3

HCID 4837PiperazineHCID 312751,4-DioxaneHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidine

Product 1

HCID 714076996-Chloro-4-(piperazin-1-yl)pyrido[3,2-d]pyrimidine

Sources & evidence

ORD record
ord-e40d07c4655d41a6a8cd4b1c9c5865c1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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