Ammonia → N-(2,6-Difluorophenyl)-5-(3-(2-(5-ethyl-4-(4-(4-(methanesulfonyl)piperazin-1-yl)piperidin-1-yl)-2-methoxyanilino)pyrimidin-4-yl)imidazo(1,2-a)pyridin-2-yl)-2-methoxybenzamide
Reaction equation
[CH2:36]([CH3:37])[c:38]1[c:39]([N:47]2[CH2:48][CH2:49][CH:50]([N:53]3[CH2:54][CH2:55][N:56]([S:59](=[O:60])(=[O:61])[CH3:62])[CH2:57][CH2:58]3)[CH2:51][CH2:52]2)[cH:40][c:41]([O:45][CH3:46])[c:42]([NH2:43])[cH:44]1.[CH3:71][OH:72].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][cH:19][c:20]([O:34][CH3:35])[c:21]([C:22](=[O:23])[NH:24][c:25]4[c:26]([F:32])[cH:27][cH:28][cH:29][c:30]4[F:31])[cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1.[ClH:63].[F:65][CH2:66][C:67]([F:68])([F:69])[OH:70].[NH3:64]>>[c:2]1([NH:43][c:42]2[c:41]([O:45][CH3:46])[cH:40][c:39]([N:47]3[CH2:48][CH2:49][CH:50]([N:53]4[CH2:54][CH2:55][N:56]([S:59](=[O:60])(=[O:61])[CH3:62])[CH2:57][CH2:58]4)[CH2:51][CH2:52]3)[c:38]([CH2:36][CH3:37])[cH:44]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][cH:19][c:20]([O:34][CH3:35])[c:21]([C:22](=[O:23])[NH:24][c:25]4[c:26]([F:32])[cH:27][cH:28][cH:29][c:30]4[F:31])[cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-64d5a378e4fb482d8d7a4e30c51b3dcf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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