O-Xylene → 4-(4-Bromophenyl)-2-(methylthio)pyrimidine
Reaction equation
[Br:22][c:23]1[cH:24][cH:25][c:26]([Br:27])[cH:28][cH:29]1.[CH3:1][S:2][c:3]1[n:4][cH:5][cH:6][c:7]([Sn:9]([CH2:10][CH2:11][CH2:12][CH3:13])([CH2:14][CH2:15][CH2:16][CH3:17])[CH2:18][CH2:19][CH2:20][CH3:21])[n:8]1.[Pd:38]([Cl:39])[Cl:40].[c:30]1([CH3:31])[c:32]([CH3:33])[cH:34][cH:35][cH:36][cH:37]1>>[CH3:1][S:2][c:3]1[n:4][cH:5][cH:6][c:7](-[c:26]2[cH:25][cH:24][c:23]([Br:22])[cH:29][cH:28]2)[n:8]1Participants
5
Sources & evidence
- ORD record
- ord-d63f7906d7fc4bea85cb6966581435c5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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