Hydrochloric Acid → 3-Fluoro-4-(5-(1-phenylcyclopent-3-enyl)-thiazolo[5,4-b]pyridine-2-yl)benzaldehyde

HRID 2147939Notes

Reaction equation

HRID 2147939 reaction equation
[ClH:34].[Na+:36].[O:1]1[CH:2]([c:7]2[cH:8][c:9]([F:33])[c:10](-[c:13]3[s:14][c:15]4[n:16][c:17]([C:22]5([c:27]6[cH:28][cH:29][cH:30][cH:31][cH:32]6)[CH2:23][CH:24]=[CH:25][CH2:26]5)[cH:18][cH:19][c:20]4[n:21]3)[cH:11][cH:12]2)[O:6][CH2:5][CH2:4][CH2:3]1.[OH-:35]>>[O:1]=[CH:2][c:7]1[cH:8][c:9]([F:33])[c:10](-[c:13]2[s:14][c:15]3[n:16][c:17]([C:22]4([c:27]5[cH:28][cH:29][cH:30][cH:31][cH:32]5)[CH2:23][CH:24]=[CH:25][CH2:26]4)[cH:18][cH:19][c:20]3[n:21]2)[cH:11][cH:12]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 671118212-(4-(1,3-Dioxan-2-yl)-2-fluorophenyl)-5-(1-phenylcyclopent-3-enyl)thiazolo[5,4-b]pyridine

Product 1

HCID 866387083-Fluoro-4-(5-(1-phenylcyclopent-3-enyl)-thiazolo[5,4-b]pyridine-2-yl)benzaldehyde

Sources & evidence

ORD record
ord-9b514546e2d64edc9703ac34fba0d24d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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