Ethanol → 2-Amino-2-(5-bromo-2-fluorophenyl)propan-1-ol

HRID 2147965Notes

Reaction equation

HRID 2147965 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([F:15])[c:6]([C:8]2([CH3:14])[NH:9][C:10](=[O:13])[O:11][CH2:12]2)[cH:7]1.[CH3:16][CH2:17][OH:18].[Li+:21].[OH-:20].[OH2:19].[OH2:22]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([F:15])[c:6]([C:8]([NH2:9])([CH2:12][OH:11])[CH3:14])[cH:7]1

Participants

6

Reactant 5

HCID 702EthanolHCID 961HydroxideHCID 962Water2×HCID 28486Lithium ionHCID 58563120(RS)-4-(5-bromo-2-fluoro-phenyl)-4-methyl-oxazolidin-2-one

Product 1

HCID 575142112-Amino-2-(5-bromo-2-fluorophenyl)propan-1-ol

Sources & evidence

ORD record
ord-628e0d890bbe4994af77141edd74f889
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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