Benzaldehyde → 4-amino-N-((1-(5-benzylaminopentyl)piperidin-4-yl)methyl)-5-chloro-2-methoxybenzamide
Reaction equation
[BH4-:35].[CH3:38][CH2:39][OH:40].[CH:1](=[O:2])[c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1.[NH2:9][c:10]1[cH:11][c:12]([O:33][CH3:34])[c:13]([C:14](=[O:15])[NH:16][CH2:17][CH:18]2[CH2:19][CH2:20][N:21]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][NH2:29])[CH2:22][CH2:23]2)[cH:30][c:31]1[Cl:32].[Na+:36].[OH2:37]>>[CH2:1]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[NH:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][N:21]1[CH2:20][CH2:19][CH:18]([CH2:17][NH:16][C:14]([c:13]2[c:12]([O:33][CH3:34])[cH:11][c:10]([NH2:9])[c:31]([Cl:32])[cH:30]2)=[O:15])[CH2:23][CH2:22]1Participants
7
Sources & evidence
- ORD record
- ord-f77ce169bd214a2f99d7363355dd8653
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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