Ethanol → 2-trimethylsilylethyl N-(2-amino-3-cyclohexylpropyl)-N-methylcarbamate

HRID 2148115Notes

Reaction equation

HRID 2148115 reaction equation
[CH2:29]([O:30][CH2:31][CH3:32])[CH3:33].[CH3:34][c:35]1[cH:36][cH:37][c:38]([S:39]([OH:40])(=[O:41])=[O:42])[cH:43][cH:44]1.[CH3:45][CH2:46][OH:47].[CH:1]1([CH2:7][CH:8]([CH2:9][N:10]([C:11](=[O:12])[O:13][CH2:14][CH2:15][Si:16]([CH3:17])([CH3:18])[CH3:19])[CH3:20])[NH:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1>>[CH:1]1([CH2:7][CH:8]([CH2:9][N:10]([C:11](=[O:12])[O:13][CH2:14][CH2:15][Si:16]([CH3:17])([CH3:18])[CH3:19])[CH3:20])[NH2:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 702EthanolHCID 3283Diethyl EtherHCID 6101p-Toluenesulfonic acidHCID 671902002-trimethylsilylethyl N-[3-cyclohexyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]propyl]-N-methylcarbamate

Product 1

HCID 667044662-trimethylsilylethyl N-(2-amino-3-cyclohexylpropyl)-N-methylcarbamate

Sources & evidence

ORD record
ord-36b931c7b3334a6397d58eb8252f18e6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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