Dimethylformamide → Ethyl 3-chloro-5-trifluoromethyl-4-cyclohexylphenylglyoxylate

HRID 2148238Notes

Reaction equation

HRID 2148238 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:15]([C:16](=[O:17])[O:18][CH2:19][CH3:20])=[O:21])[cH:5][c:6]([Cl:14])[c:7]1[CH:8]1[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]1.[CH3:28][N:29]([CH3:30])[CH:31]=[O:32].[Cu:27].[F:22][C:23]([F:24])([F:25])[I:26]>>[c:2]1([C:23]([F:22])([F:24])[F:25])[cH:3][c:4]([C:15]([C:16](=[O:17])[O:18][CH2:19][CH3:20])=[O:21])[cH:5][c:6]([Cl:14])[c:7]1[CH:8]1[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 16843TrifluoroiodomethaneHCID 23978CopperHCID 20515177Ethyl 3-bromo-5-chloro-4-cyclohexylphenylglyoxylate

Product 1

HCID 20515171Ethyl 3-chloro-5-trifluoromethyl-4-cyclohexylphenylglyoxylate

Sources & evidence

ORD record
ord-e12f0c30983c49c6845353f311cb2445
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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