1-(1-Naphthyl)piperazine → 3-Ethylthio-5-fluoro-3-(2-[4-(1-naphthyl)-1-piperazinyl]ethyl}-1,3-dihydro-2(2H)-indolone
Reaction equation
[CH2:28]([CH3:29])[S:30][C:31]1([CH2:42][CH2:43][OH:44])[C:32](=[O:41])[NH:33][c:34]2[cH:35][cH:36][c:37]([F:40])[cH:38][c:39]21.[OH:17][S:18]([c:19]1[cH:20][cH:21][c:22]([CH3:23])[cH:24][cH:25]1)(=[O:26])=[O:27].[c:1]1([N:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[cH:2][cH:3][cH:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]12>>[c:1]1([N:11]2[CH2:12][CH2:13][N:14]([CH2:43][CH2:42][C:31]3([S:30][CH2:28][CH3:29])[C:32](=[O:41])[NH:33][c:34]4[cH:35][cH:36][c:37]([F:40])[cH:38][c:39]43)[CH2:15][CH2:16]2)[cH:2][cH:3][cH:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]12Participants
4
Sources & evidence
- ORD record
- ord-dfee54d7b9c14e729f3e6827cf1eba37
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…