Methanol → Benzyl 4-[[1-[3-(4-methylsulfonylphenyl)propyl]piperidin-3-yl]methyl]piperazine-1-carboxylate
Reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8]([CH2:11][CH2:12][CH2:13][OH:14])[cH:9][cH:10]1.[CH3:52][OH:53].[Cl:49][CH2:50][Cl:51].[Mg+2:43].[NH:20]1[CH2:21][CH:22]([CH2:26][N:27]2[CH2:28][CH2:29][N:30]([C:33](=[O:34])[O:35][CH2:36][c:37]3[cH:38][cH:39][cH:40][cH:41][cH:42]3)[CH2:31][CH2:32]2)[CH2:23][CH2:24][CH2:25]1.[O-:15][I+3:16]([O-:17])([O-:18])[O-:19].[O-:44][S:45](=[O:46])(=[O:47])[O-:48]>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8]([CH2:11][CH2:12][CH2:13][N:20]2[CH2:21][CH:22]([CH2:26][N:27]3[CH2:28][CH2:29][N:30]([C:33](=[O:34])[O:35][CH2:36][c:37]4[cH:38][cH:39][cH:40][cH:41][cH:42]4)[CH2:31][CH2:32]3)[CH2:23][CH2:24][CH2:25]2)[cH:9][cH:10]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-25a58d2cb8a44fa8b8f4f2c7d44d64d7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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