Chloroform → Hydrochloric Acid

HRID 2148501Notes

Reaction equation

HRID 2148501 reaction equation
[CH:33]([Cl:34])([Cl:35])[Cl:36].[F:19][C:20]([c:21]1[cH:22][cH:23][c:24]([CH2:27][C:28](=[O:29])[Cl:30])[cH:25][cH:26]1)([F:31])[F:32].[N:1]1([CH2:6][CH:7]2[NH:8][CH2:9][CH2:10][c:11]3[c:12]([O:17][CH3:18])[cH:13][cH:14][cH:15][c:16]32)[CH2:2][CH2:3][CH2:4][CH2:5]1>>[ClH:30].[N:1]1([CH2:6][C:7]2([C:28]([CH2:27][c:24]3[cH:23][cH:22][c:21]([C:20]([F:19])([F:31])[F:32])[cH:26][cH:25]3)=[O:29])[NH:8][CH2:9][CH2:10][c:11]3[c:12]([O:17][CH3:18])[cH:13][cH:14][cH:15][c:16]32)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

5

Reactant 3

HCID 6212ChloroformHCID 148109432-(4-(Trifluoromethyl)phenyl)acetyl chlorideHCID 15005443HCID 15005443, compound

Product 2

HCID 313Hydrochloric AcidHCID 678696791-[5-methoxy-1-(pyrrolidin-1-ylmethyl)-3,4-dihydro-2H-isoquinolin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone

Sources & evidence

ORD record
ord-0b3bfe8863bc49d7be459b1eb7b43ad5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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