Ammonia → 6-(1-Cyclopropyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d]pyrimidin-4-amine

HRID 2148523Notes

Reaction equation

HRID 2148523 reaction equation
[CH:1]1([n:4]2[cH:5][n:6][c:7](-[c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[c:8]2-[c:9]2[cH:10][c:11]3[c:12]([n:13][cH:14][n:15][c:16]3[S:17][CH3:18])[s:19]2)[CH2:2][CH2:3]1.[Cl-:27].[Cl:35][CH2:36][Cl:37].[NH3:26].[NH4+:28].[O:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1.[OH2:38]>>[CH:1]1([n:4]2[cH:5][n:6][c:7](-[c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[c:8]2-[c:9]2[cH:10][c:11]3[c:12]([n:13][cH:14][n:15][c:16]3[NH2:26])[s:19]2)[CH2:2][CH2:3]1

Participants

8

Reactant 7

HCID 222AmmoniaHCID 223AmmoniumHCID 312ChlorideHCID 962WaterHCID 6344DichloromethaneHCID 312751,4-DioxaneHCID 691961746-(1-cyclopropyl-4-phenyl-1H-imidazol-5-yl)-4-(methylthio)thieno[2,3-d]pyrimidine

Product 1

HCID 103369216-(1-Cyclopropyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-a6361cd520044c95993edc0cf75b5780
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…