Dimethyl Sulfoxide → 4-(3-(Trifluoromethyl)pyridin-2-yl)piperazin-2-one
Reaction equation
[CH3:28][S:29]([CH3:30])=[O:31].[CH:19]([N:20]([CH:21]([CH3:22])[CH3:23])[CH2:24][CH3:25])([CH3:26])[CH3:27].[Cl:8][c:9]1[n:10][cH:11][cH:12][cH:13][c:14]1[C:15]([F:16])([F:17])[F:18].[NH:1]1[C:2](=[O:7])[CH2:3][NH:4][CH2:5][CH2:6]1.[OH2:32]>>[NH:1]1[C:2](=[O:7])[CH2:3][N:4]([c:9]2[n:10][cH:11][cH:12][cH:13][c:14]2[C:15]([F:16])([F:17])[F:18])[CH2:5][CH2:6]1Participants
6
Sources & evidence
- ORD record
- ord-2140e272cfd94beab1ffa25fa4ba5586
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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