Bromide ion → 2-[5-(2,4-Diaminopyrimidin-5-yloxy)-4-isopropyl-2-methoxy-phenyl]-propan-2-ol
Reaction equation
[Br-:1].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:2][Mg+:3].[I:33][CH3:34].[K+:27].[K+:28].[NH2:4][c:5]1[n:6][cH:7][c:8]([O:12][c:13]2[c:14]([CH:24]([CH3:25])[CH3:26])[cH:15][c:16]([O:22][CH3:23])[c:17]([C:19]([CH3:20])=[O:21])[cH:18]2)[c:9]([NH2:11])[n:10]1.[O-:29][C:30]([O-:31])=[O:32]>>[NH2:4][c:5]1[n:6][cH:7][c:8]([O:12][c:13]2[c:14]([CH:24]([CH3:25])[CH3:26])[cH:15][c:16]([O:22][CH3:23])[c:17]([C:19]([CH3:20])([OH:21])[CH3:30])[cH:18]2)[c:9]([NH2:11])[n:10]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e5b3d6020674464fbc4a155341e2ab94
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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