Hydrochloric Acid → 1-Cyclopropyl-3-(2-fluoro-4-iodo-phenylamino)-1H-pyrrolo[32-c]pyridine-2-carboxylic acid (2,3-dihydroxy-propoxy)-amide

HRID 214897Notes

Reaction equation

HRID 214897 reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][O:41][CH2:42]1.[CH3:1][C:2]1([CH3:33])[O:3][CH2:4][CH:5]([CH2:7][O:8][NH:9][C:10](=[O:11])[c:12]2[c:13]([NH:24][c:25]3[c:26]([F:32])[cH:27][c:28]([I:31])[cH:29][cH:30]3)[c:14]3[cH:15][n:16][cH:17][cH:18][c:19]3[n:20]2[CH:21]2[CH2:22][CH2:23]2)[O:6]1.[CH3:35][OH:36].[ClH:34]>>[OH:3][CH2:4][CH:5]([OH:6])[CH2:7][O:8][NH:9][C:10](=[O:11])[c:12]1[c:13]([NH:24][c:25]2[c:26]([F:32])[cH:27][c:28]([I:31])[cH:29][cH:30]2)[c:14]2[cH:15][n:16][cH:17][cH:18][c:19]2[n:20]1[CH:21]1[CH2:22][CH2:23]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 312751,4-DioxaneHCID 595965981-cyclopropyl-3-(2-fluoro-4-iodo-phenylamino)-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid (2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-amide

Product 1

HCID 595966111-Cyclopropyl-3-(2-fluoro-4-iodo-phenylamino)-1H-pyrrolo[32-c]pyridine-2-carboxylic acid (2,3-dihydroxy-propoxy)-amide

Sources & evidence

ORD record
ord-9fd0758c8cc14b038e47a69805826fb9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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