Dimethyl Sulfoxide → Isopropyl 4-(6-(2,4-dimethyl-6-(methylsulfonyl)pyridin-3-ylamino)-5-methoxypyrimidin-4-yloxy)piperidine-1-carboxy-late
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH3:31])[c:5]([NH:9][c:10]2[c:11]([O:29][CH3:30])[c:12]([O:16][CH:17]3[CH2:18][CH2:19][N:20]([C:23](=[O:24])[O:25][CH:26]([CH3:27])[CH3:28])[CH2:21][CH2:22]3)[n:13][cH:14][n:15]2)[c:6]([CH3:8])[n:7]1.[CH3:37][S:38]([CH3:39])=[O:40].[Na:32].[OH2:36].[SH:33]([O-:34])=[O:35]>>[c:2]1([S:33](=[O:34])(=[O:35])[CH3:37])[cH:3][c:4]([CH3:31])[c:5]([NH:9][c:10]2[c:11]([O:29][CH3:30])[c:12]([O:16][CH:17]3[CH2:18][CH2:19][N:20]([C:23](=[O:24])[O:25][CH:26]([CH3:27])[CH3:28])[CH2:21][CH2:22]3)[n:13][cH:14][n:15]2)[c:6]([CH3:8])[n:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-94e79b17ed794c60a0d4269e5ff19308
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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