Acetonitrile → 3-[4-(Formyl)phenyl]-5-(4-phenyl-5-trifluoromethyl-2-thienyl)-1,2,4-oxadiazole

HRID 214908Notes

Reaction equation

HRID 214908 reaction equation
[CH3:29][N+:30]1([O-:31])[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1.[CH3:37][C:38]#[N:39].[CH3:45][CH2:46][CH2:47][N+:48]([CH2:49][CH2:50][CH3:51])([CH2:52][CH2:53][CH3:54])[CH2:55][CH2:56][CH3:57].[O-:40][Ru:41](=[O:42])(=[O:43])=[O:44].[OH:1][CH2:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[n:10][o:11][c:12](-[c:14]3[s:15][c:16]([C:25]([F:26])([F:27])[F:28])[c:17](-[c:19]4[cH:20][cH:21][cH:22][cH:23][cH:24]4)[cH:18]3)[n:13]2)[cH:7][cH:8]1>>[O:1]=[CH:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[n:10][o:11][c:12](-[c:14]3[s:15][c:16]([C:25]([F:26])([F:27])[F:28])[c:17](-[c:19]4[cH:20][cH:21][cH:22][cH:23][cH:24]4)[cH:18]3)[n:13]2)[cH:7][cH:8]1

Participants

6

Reactant 5

HCID 6342AcetonitrileHCID 9559TetrapropylammoniumHCID 82029Methyl morpholine oxideHCID 111538793-[4-(Hydroxymethyl)phenyl]-5-(4-phenyl-5-trifluoromethyl-2-thienyl)-1,2,4-oxadiazoleHCID 178527104HCID 178527104, compound

Product 1

HCID 112117363-[4-(Formyl)phenyl]-5-(4-phenyl-5-trifluoromethyl-2-thienyl)-1,2,4-oxadiazole

Sources & evidence

ORD record
ord-9785e88f5d034afea9a49c55cd35f562
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…