Water → Ethyl 2-(4-amino-3-chloro-5-(2,2,2-trifluoroethoxy)phenyl)-4-methylpentanoate

HRID 2149308Notes

Reaction equation

HRID 2149308 reaction equation
[Cl:24][N:25]1[C:26](=[O:27])[CH2:28][CH2:29][C:30]1=[O:31].[Cl:32][CH:33]([Cl:34])[Cl:35].[NH2:1][c:2]1[c:3]([O:18][CH2:19][C:20]([F:21])([F:22])[F:23])[cH:4][c:5]([CH:8]([C:9](=[O:10])[O:11][CH2:12][CH3:13])[CH2:14][CH:15]([CH3:16])[CH3:17])[cH:6][cH:7]1.[OH2:36]>>[NH2:1][c:2]1[c:3]([O:18][CH2:19][C:20]([F:21])([F:22])[F:23])[cH:4][c:5]([CH:8]([C:9](=[O:10])[O:11][CH2:12][CH3:13])[CH2:14][CH:15]([CH3:16])[CH3:17])[cH:6][c:7]1[Cl:24]

Participants

5

Reactant 4

HCID 962WaterHCID 6212ChloroformHCID 31398ChlorosuccinimideHCID 57995581Ethyl 2-(4-amino-3-(2,2,2-trifluoroethoxy)phenyl)-4-methylpentanoate

Product 1

HCID 57995604Ethyl 2-(4-amino-3-chloro-5-(2,2,2-trifluoroethoxy)phenyl)-4-methylpentanoate

Sources & evidence

ORD record
ord-87b36ee8190c4e508aca19970991cffc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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