Hydrochloric Acid → 4-Amino-5-chloro-N-(1-(4-(2,3-dihydro-1,3-dioxo-1H-isoindol-2-yl)butyl)piperidin-4-ylmethyl)-2-methoxybenzamide

HRID 2149704Notes

Reaction equation

HRID 2149704 reaction equation
[Br:23][CH2:24][CH2:25][CH2:26][CH2:27][N:28]1[C:29](=[O:38])[c:30]2[c:31]([cH:34][cH:35][cH:36][cH:37]2)[C:32]1=[O:33].[ClH:1].[ClH:2].[NH2:3][c:4]1[cH:5][c:6]([O:21][CH3:22])[c:7]([C:8](=[O:9])[NH:10][CH2:11][CH:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[cH:18][c:19]1[Cl:20]>>[NH2:3][c:4]1[cH:5][c:6]([O:21][CH3:22])[c:7]([C:8](=[O:9])[NH:10][CH2:11][CH:12]2[CH2:13][CH2:14][N:15]([CH2:24][CH2:25][CH2:26][CH2:27][N:28]3[C:29](=[O:38])[c:30]4[c:31]([cH:34][cH:35][cH:36][cH:37]4)[C:32]3=[O:33])[CH2:16][CH2:17]2)[cH:18][c:19]1[Cl:20]

Participants

4

Reactant 3

HCID 313Hydrochloric Acid2×HCID 93575N-(4-Bromobutyl)phthalimideHCID 98177134-amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide

Product 1

HCID 539169944-Amino-5-chloro-N-(1-(4-(2,3-dihydro-1,3-dioxo-1H-isoindol-2-yl)butyl)piperidin-4-ylmethyl)-2-methoxybenzamide

Sources & evidence

ORD record
ord-4b41a83a811a4fbd9836dcaa61eeac7e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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