Methanol → 4-[4-[3-[1-(2-chloro-3-fluoro-6-methoxyphenyl)ethyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-3,5-dimethylpyrazol-1-yl]cyclohexane-1-carboxylic acid
Reaction equation
[CH3:40][OH:41].[Cl:1][c:2]1[c:3]([CH:11]([CH3:12])[c:13]2[cH:14][nH:15][c:16]3[n:17][cH:18][c:19](-[c:22]4[c:23]([CH3:39])[n:24][n:25]([CH:28]5[CH2:29][CH2:30][CH:31]([C:34](=[O:35])[O:36][CH2:37][CH3:38])[CH2:32][CH2:33]5)[c:26]4[CH3:27])[cH:20][c:21]23)[c:4]([O:9][CH3:10])[cH:5][cH:6][c:7]1[F:8].[Li+:42].[OH-:43].[OH2:44]>>[Cl:1][c:2]1[c:3]([CH:11]([CH3:12])[c:13]2[cH:14][nH:15][c:16]3[n:17][cH:18][c:19](-[c:22]4[c:23]([CH3:39])[n:24][n:25]([CH:28]5[CH2:29][CH2:30][CH:31]([C:34](=[O:35])[OH:36])[CH2:32][CH2:33]5)[c:26]4[CH3:27])[cH:20][c:21]23)[c:4]([O:9][CH3:10])[cH:5][cH:6][c:7]1[F:8]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-2bdfbface7144707a2330c7521a96e10
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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