Dichloromethane → 2-[7-(2-Fluoro-phenyl)-4-oxo-4,5-dihydro-1H-benzo[b][1,4]diazepin-2-yl]-thiophene-3-carbonitrile
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:21][C:22]([CH2:23][C:24](=[O:5])[c:26]2[s:27][cH:28][cH:29][c:30]2[C:31]#[N:32])=[O:33])[cH:10][c:11](-[c:14]2[c:15]([F:20])[cH:16][cH:17][cH:18][cH:19]2)[cH:12][cH:13]1)([CH3:6])([CH3:25])[CH3:34].[Cl:42][CH2:43][Cl:44].[F:35][C:36]([F:37])([F:38])[C:39]([OH:40])=[O:41]>>[NH:7]1[c:8]2[c:9]([cH:10][c:11](-[c:14]3[c:15]([F:20])[cH:16][cH:17][cH:18][cH:19]3)[cH:12][cH:13]2)[NH:21][C:22](=[O:33])[CH:23]=[C:24]1[c:26]1[s:27][cH:28][cH:29][c:30]1[C:31]#[N:32]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-cff3f98e70294fb9987b4f8c4813173f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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