Methanol → N-[1-amino-3-[2-(trifluoromethyl)phenyl]propan-2-yl]-4-(4-chloro-1-methylpyrazol-5-yl)-5-ethylthiophene-2-carboxamide
Reaction equation
[CH3:49][OH:50].[Cl:1][c:2]1[cH:3][n:4][n:5]([CH3:41])[c:6]1-[c:7]1[cH:8][c:9]([C:14](=[O:15])[NH:16][CH:17]([CH2:18][N:19]2[C:20](=[O:21])[c:22]3[c:23]([cH:24][cH:25][cH:26][cH:27]3)[C:28]2=[O:29])[CH2:30][c:31]2[c:32]([C:37]([F:38])([F:39])[F:40])[cH:33][cH:34][cH:35][cH:36]2)[s:10][c:11]1[CH2:12][CH3:13].[NH2:42][NH2:43].[O:44]1[CH2:45][CH2:46][CH2:47][CH2:48]1>>[Cl:1][c:2]1[cH:3][n:4][n:5]([CH3:41])[c:6]1-[c:7]1[cH:8][c:9]([C:14](=[O:15])[NH:16][CH:17]([CH2:18][NH2:19])[CH2:30][c:31]2[c:32]([C:37]([F:38])([F:39])[F:40])[cH:33][cH:34][cH:35][cH:36]2)[s:10][c:11]1[CH2:12][CH3:13]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-6582b68faea742108fbbe084eb60e929
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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