2-Amino-5-methylpyridine → 2-Hydroxymethyl-4-(4-methanesulfonyl-phenoxy)-2-methyl-2,3-dihydro-benzofuran-6-carboxylic acid (5-methyl-pyridin-2-yl)-amide

HRID 2150031Notes

Reaction equation

HRID 2150031 reaction equation
[C:1]([CH3:3])([CH3:4])([O:5][C:6](=[O:2])[c:8]1[cH:9][c:10]2[c:11]([c:18]([O:20][c:21]3[cH:22][cH:23][c:24]([S:27](=[O:28])(=[O:29])[CH3:30])[cH:25][cH:26]3)[cH:19]1)[CH2:12][C:13]([CH3:15])([CH2:16][OH:17])[O:14]2)[CH3:7].[CH3:31][c:32]1[cH:33][cH:34][c:35]([NH2:38])[n:36][cH:37]1>>[O:5]=[C:6]([c:8]1[cH:9][c:10]2[c:11]([c:18]([O:20][c:21]3[cH:22][cH:23][c:24]([S:27](=[O:28])(=[O:29])[CH3:30])[cH:25][cH:26]3)[cH:19]1)[CH2:12][C:13]([CH3:15])([CH2:16][OH:17])[O:14]2)[NH:38][c:35]1[cH:34][cH:33][c:32]([CH3:31])[cH:37][n:36]1

Participants

3

Reactant 2

HCID 153482-Amino-5-methylpyridineHCID 595598582-Hydroxymethyl-4-(4-methanesulfonyl-phenoxy)-2-methyl-2,3-dihydro-benzofuran-6-carboxylic acid tert-butyl ester

Product 1

HCID 595600442-Hydroxymethyl-4-(4-methanesulfonyl-phenoxy)-2-methyl-2,3-dihydro-benzofuran-6-carboxylic acid (5-methyl-pyridin-2-yl)-amide

Sources & evidence

ORD record
ord-738189afbe004d00ba321ce82b7372ee
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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