Hydrochloric Acid → N-(2-aminoethyl)-N-[(4-chlorophenyl)methyl]-4-(5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine-1-carboxamide

HRID 2150160Notes

Reaction equation

HRID 2150160 reaction equation
[CH3:45][OH:46].[Cl:8][c:9]1[cH:10][cH:11][c:12]([CH2:13][N:14]([C:15](=[O:16])[N:17]2[CH2:18][CH2:19][N:20]([c:23]3[c:24]4[c:25]([n:26][cH:27][n:28]3)[CH2:29][CH2:30][CH:31]4[CH3:32])[CH2:21][CH2:22]2)[CH2:33][CH2:34][NH:35][C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[cH:43][cH:44]1.[ClH:1].[O:2]1[CH2:3][CH2:4][O:5][CH2:6][CH2:7]1>>[Cl:8][c:9]1[cH:10][cH:11][c:12]([CH2:13][N:14]([C:15](=[O:16])[N:17]2[CH2:18][CH2:19][N:20]([c:23]3[c:24]4[c:25]([n:26][cH:27][n:28]3)[CH2:29][CH2:30][CH:31]4[CH3:32])[CH2:21][CH2:22]2)[CH2:33][CH2:34][NH2:35])[cH:43][cH:44]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 312751,4-DioxaneHCID 67134585tert-butyl N-[2-[(4-chlorophenyl)methyl-[4-(5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine-1-carbonyl]amino]ethyl]carbamate

Product 1

HCID 67133905N-(2-aminoethyl)-N-[(4-chlorophenyl)methyl]-4-(5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine-1-carboxamide

Sources & evidence

ORD record
ord-d90397fa43114b90b75bd76b9cb7bd31
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…