Sodium ion → Tert-butyl 4-(4-cyanophenyl)piperidine-1-carboxylate

HRID 2150263Notes

Reaction equation

HRID 2150263 reaction equation
[NH2:1][C:2](=[O:3])[c:4]1[cH:5][cH:6][c:7]([CH:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[cH:8][cH:9]1.[Na+:29].[Na+:30].[O-:31][C:32](=[O:33])[O-:34].[O:35]=[CH:36][N:37]([CH3:38])[CH3:39].[P:23]([Cl:24])([Cl:25])([O:26][Cl:27])=[O:28]>>[N:1]#[C:2][c:4]1[cH:5][cH:6][c:7]([CH:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[cH:8][cH:9]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 224929041,1-Dimethylethyl 4-[4-(aminocarbonyl)phenyl]-1-piperidinecarboxylateHCID 86587839Phosphoryloxychloride

Product 1

HCID 22492960Tert-butyl 4-(4-cyanophenyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-32df7067899249589669511fa99e7c79
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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