Borane → 1-[4-(3,4-Difluorophenoxy)piperidin-1-yl]-3-phenylpropan-2-amine
Reaction equation
[BH3:27].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH:8]([C:9](=[O:10])[N:11]1[CH2:12][CH2:13][CH:14]([O:17][c:18]2[cH:19][c:20]([F:25])[c:21]([F:24])[cH:22][cH:23]2)[CH2:15][CH2:16]1)[NH2:26].[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH:8]([CH2:9][N:11]1[CH2:12][CH2:13][CH:14]([O:17][c:18]2[cH:19][c:20]([F:25])[c:21]([F:24])[cH:22][cH:23]2)[CH2:15][CH2:16]1)[NH2:26]Participants
4
Sources & evidence
- ORD record
- ord-4b107317673f45eb95429588dea95301
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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