Tetrahydrofuran → Methyl 4'-(4-bromo-5-chloropyridin-2-ylamino)-5'-methoxy-2'-methylbiphenyl-4-carboxylate
Reaction equation
[Br:21][c:22]1[n:23][cH:24][c:25]([Cl:29])[c:26]([Br:28])[cH:27]1.[C:30](=[O:31])([O-:32])[O-:33].[CH2:92]1[O:93][CH2:94][CH2:95][CH2:96]1.[Cs+:34].[Cs+:35].[NH2:1][c:2]1[cH:3][c:4]([CH3:20])[c:5](-[c:10]2[cH:11][cH:12][c:13]([C:16](=[O:17])[O:18][CH3:19])[cH:14][cH:15]2)[cH:6][c:7]1[O:8][CH3:9].[O:38]=[C:39]([CH:40]=[CH:41][c:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1)[CH:48]=[CH:49][c:50]1[cH:51][cH:52][cH:53][cH:54][cH:55]1.[O:56]=[C:57]([CH:58]=[CH:59][c:60]1[cH:61][cH:62][cH:63][cH:64][cH:65]1)[CH:66]=[CH:67][c:68]1[cH:69][cH:70][cH:71][cH:72][cH:73]1.[O:74]=[C:75]([CH:76]=[CH:77][c:78]1[cH:79][cH:80][cH:81][cH:82][cH:83]1)[CH:84]=[CH:85][c:86]1[cH:87][cH:88][cH:89][cH:90][cH:91]1.[Pd:36].[Pd:37]>>[NH:1]([c:2]1[cH:3][c:4]([CH3:20])[c:5](-[c:10]2[cH:11][cH:12][c:13]([C:16](=[O:17])[O:18][CH3:19])[cH:14][cH:15]2)[cH:6][c:7]1[O:8][CH3:9])[c:22]1[n:23][cH:24][c:25]([Cl:29])[c:26]([Br:28])[cH:27]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e9b8c09c6fcd46b0aebad3c13bad95f7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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