1-Propanol → 4-chloro-N-({4-chloro-3-[(3-chloro-5-ethenylphenyl)oxy]-2-fluorophenyl}methyl)-1-({[2-(trimethylsilyl)ethyl]oxy}methyl)-1H-imidazole-5-carboxamide

HRID 2150606Notes

Reaction equation

HRID 2150606 reaction equation
[Br:1][c:2]1[cH:3][c:4]([O:9][c:10]2[c:11]([F:35])[c:12]([CH2:17][NH:18][C:19](=[O:20])[c:21]3[c:22]([Cl:34])[n:23][cH:24][n:25]3[CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:31])([CH3:32])[CH3:33])[cH:13][cH:14][c:15]2[Cl:16])[cH:5][c:6]([Cl:8])[cH:7]1.[CH2:36]([CH2:37][CH3:39])[OH:38]>>[c:2]1([CH:36]=[CH2:37])[cH:3][c:4]([O:9][c:10]2[c:11]([F:35])[c:12]([CH2:17][NH:18][C:19](=[O:20])[c:21]3[c:22]([Cl:34])[n:23][cH:24][n:25]3[CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:31])([CH3:32])[CH3:33])[cH:13][cH:14][c:15]2[Cl:16])[cH:5][c:6]([Cl:8])[cH:7]1

Participants

3

Reactant 2

HCID 10311-PropanolHCID 68487164N-({3-[(3-bromo-5-chlorophenyl)oxy]-4-chloro-2-fluorophenyl}methyl)-4-chloro-1-({[2-(trimethylsilyl)ethyl]oxy}methyl)-1H-imidazole-5-carboxamide

Product 1

HCID 684897804-chloro-N-({4-chloro-3-[(3-chloro-5-ethenylphenyl)oxy]-2-fluorophenyl}methyl)-1-({[2-(trimethylsilyl)ethyl]oxy}methyl)-1H-imidazole-5-carboxamide

Sources & evidence

ORD record
ord-33b9a6870164414e8319d4439f94502a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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