Hydrochloric Acid → 1-[2-(4-Aminopiperidin-1-yl)ethyl]quinolin-2(1H)-one

HRID 215071Notes

Reaction equation

HRID 215071 reaction equation
[ClH:28].[ClH:30].[O:1]=[c:2]1[n:3]([CH2:12][CH2:13][N:14]2[CH2:15][CH2:16][CH:17]([NH:20][C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:18][CH2:19]2)[c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[cH:10][cH:11]1.[O:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1.[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1.[OH2:29]>>[O:1]=[c:2]1[n:3]([CH2:12][CH2:13][N:14]2[CH2:15][CH2:16][CH:17]([NH2:20])[CH2:18][CH2:19]2)[c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[cH:10][cH:11]1

Participants

5

Reactant 4

HCID 313Hydrochloric Acid2×HCID 962WaterHCID 312751,4-Dioxane2×HCID 86642648tert-butyl{1-[2-(2-oxoquinolin-1(2H)-yl)ethyl]piperidin-4-yl}carbamate

Product 1

HCID 667749211-[2-(4-Aminopiperidin-1-yl)ethyl]quinolin-2(1H)-one

Sources & evidence

ORD record
ord-0cd23d8c13754eea9c50228bf3a27cfd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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